Cannabinoid CB2 receptor agonist reduces local and systemic inflammation associated with pneumonia-induced sepsis in mice
Eur J Pharmacol. 2023 Oct 3:176092. doi: 10.1016/j.ejphar.2023.176092. Online ahead of print. ABSTRACT Sepsis is a severe condition secondary to dysregulated host response to infection...
Self-reported substance use with clinician interviewers versus self-administered surveys
J Stud Alcohol Drugs. 2023 Oct 3. doi: 10.15288/jsad.23-00004. Online ahead of print. ABSTRACT OBJECTIVE: Underreporting of substance use is a frequent concern about studies...
Tobacco and Illicit Drug Use and Drug Use Disorders Among Employees of Businesses Affected by the 9/11 Attacks on the World Trade Center in New York CityPOST-9/11 TOBACCO USE AND DRUG USE/DISORDERS
J Dual Diagn. 2023 Oct 5:1-9. doi: 10.1080/15504263.2023.2260328. Online ahead of print. ABSTRACT Objective: To study the New York City area population after the September...
Assessing the associations between known genetic variants and substance use in people with HIV in the United States
PLoS One. 2023 Oct 5;18(10):e0292068. doi: 10.1371/journal.pone.0292068. eCollection 2023. ABSTRACT BACKGROUND: The prevalence of substance use in people with HIV (PWH) in the United States...
Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3 is mediated by apoptotic cell death, NFκB activation, increased oxidative stress, and lower reduced glutathione status
PLoS One. 2023 Oct 5;18(10):e0286758. doi: 10.1371/journal.pone.0286758. eCollection 2023. ABSTRACT Prostate cancer is the second most frequent cancer diagnosed in men in the world today....
Validation and Quantitation of Fifteen Cannabinoids in Cannabis and Marketed Products Using High-Performance Liquid Chromatography-Ultraviolet/Photodiode Array Method
Cannabis Cannabinoid Res. 2023 Oct 5. doi: 10.1089/can.2022.0335. Online ahead of print. ABSTRACT Background: Cannabis sativa is a psychoactive plant indigenous to Central and South...
Changes in Cannabis-Attributable Hospitalizations Following Nonmedical Cannabis Legalization in Canada
JAMA Netw Open. 2023 Oct 2;6(10):e2336113. doi: 10.1001/jamanetworkopen.2023.36113. ABSTRACT IMPORTANCE: The impact of adult-use cannabis legalization and subsequent commercialization (ie, increasing store and product access)...
Refactoring the architecture of a polyketide gene cluster enhances docosahexaenoic acid production in Yarrowia lipolytica through improved expression and genetic stability
Microb Cell Fact. 2023 Sep 29;22(1):199. doi: 10.1186/s12934-023-02209-9. ABSTRACT BACKGROUND: Long-chain polyunsaturated fatty acids (LC-PUFAs), such as docosahexaenoic acid (DHA), are essential for human health...
Cannabis Hunger Games: nutrient stress induction in flowering stage – impact of organic and mineral fertilizer levels on biomass, cannabidiol (CBD) yield and nutrient use efficiency
Front Plant Sci. 2023 Sep 19;14:1233232. doi: 10.3389/fpls.2023.1233232. eCollection 2023. ABSTRACT Indoor medicinal cannabis cultivation systems enable year-round cultivation and better control of growing factors,...
DNA vaccine incorporated poly (lactic-co-glycolic) acid (PLGA) microspheres offer enhanced protection against Aeromonas hydrophila infection
Int J Biol Macromol. 2023 Oct 2:127182. doi: 10.1016/j.ijbiomac.2023.127182. Online ahead of print. ABSTRACT Encapsulation of DNA vaccines onto carriers enhances the immunogenicity of an...
A two-sample approach to retrograde extrapolation of blood THC concentrations – Is it feasible?
Forensic Sci Int. 2023 Sep 22;352:111833. doi: 10.1016/j.forsciint.2023.111833. Online ahead of print. ABSTRACT BACKGROUND: Retrograde extrapolation of drug concentrations in blood can be relevant in...
Knowledge of Cannabinoid Content Among People Living with HIV Who Use Cannabis: a Daily Diary Study
Int J Behav Med. 2023 Oct 4. doi: 10.1007/s12529-023-10221-x. Online ahead of print. ABSTRACT BACKGROUND: Many people living with HIV (PLWH) use cannabis for medicinal...
Bridging the Binding Sites 2.0: Photoswitchable Dualsteric Ligands for the Cannabinoid 2 Receptor
ACS Chem Neurosci. 2023 Oct 4. doi: 10.1021/acschemneuro.3c00509. Online ahead of print. ABSTRACT The cannabinoid receptor 2 (CB2R) has high, unexploited therapeutic potential in several...
Eicosapentaenoic Acid Influences the Lipid Profile of an In Vitro Psoriatic Skin Model Produced with T Cells
Biomolecules. 2023 Sep 19;13(9):1413. doi: 10.3390/biom13091413. ABSTRACT Psoriasis is a skin disease characterized by epidermal hyperplasia and an inappropriate activation of the adaptive immunity. A...
Infection, Inflammation, and Immunity in Sepsis
Biomolecules. 2023 Aug 31;13(9):1332. doi: 10.3390/biom13091332. ABSTRACT Sepsis is triggered by microbial infection, injury, or even major surgery. Both innate and adaptive immune systems are...