Crystalline silica-induced proinflammatory eicosanoid storm in novel alveolar macrophage model quelled by docosahexaenoic acid supplementation
Front Immunol. 2023 Nov 9;14:1274147. doi: 10.3389/fimmu.2023.1274147. eCollection 2023. ABSTRACT INTRODUCTION: Phagocytosis of inhaled crystalline silica (cSiO2) particles by tissue-resident alveolar macrophages (AMs) initiates generation...
Gamma-rays induced mutations increase soybean oil and protein contents
PeerJ. 2023 Nov 21;11:e16395. doi: 10.7717/peerj.16395. eCollection 2023. ABSTRACT Mutation breeding is one of the effective techniques used for improving desired traits such as yield...
Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol
BMJ Open. 2023 Nov 29;13(11):e077427. doi: 10.1136/bmjopen-2023-077427. ABSTRACT INTRODUCTION: There remains an unmet need for safe and cost-effective adjunctive treatment of advanced colorectal cancer (CRC)....
Dietary puerarin supplementation improves immune function in the small intestines of oxidized oil-challenged broilers
Anim Sci J. 2023 Jan-Dec;94(1):e13895. doi: 10.1111/asj.13895. ABSTRACT Puerarin has possessed a wide range of pharmacological activities. However, little is known about the protective effects...
Detection in seized samples, analytical characterization, and in vitro metabolism of the newly emerged 5-bromo-indazole-3-carboxamide synthetic cannabinoid receptor agonists
Drug Test Anal. 2023 Nov 30. doi: 10.1002/dta.3609. Online ahead of print. ABSTRACT Synthetic cannabinoid receptor agonists (SCRAs) are a diverse class of new psychoactive...
11-Nor-9-Carboxy-Δ8-Tetrahydrocannabinol, 7-Carboxy Cannabidiol, and 11-Nor-9-Carboxy-Δ9-Tetrahydrocannabinol in Urine by LC-MS/MS
Methods Mol Biol. 2024;2737:161-174. doi: 10.1007/978-1-0716-3541-4_16. ABSTRACT Δ8-Tetrahydrocannabinol (Δ8-THC) and cannabidiol (CBD) are increasingly popular cannabinoids. Measuring metabolites in urine is an important tool for...
A Direct Dilute-and-Shoot HPLC-MS/MS Method for Tetrahydrocannabinol (THC) Metabolites
Methods Mol Biol. 2024;2737:435-442. doi: 10.1007/978-1-0716-3541-4_40. ABSTRACT The Cannabis plant has been smoked for medicinal and recreational purposes for thousands of years. Tetrahydrocannabinol (THC) is...
A comparative analysis of morphology, microstructure, and volatile metabolomics of leaves at varied developmental stages in Ainaxiang (Blumea balsamifera (Linn.) DC.)
Front Plant Sci. 2023 Nov 14;14:1285616. doi: 10.3389/fpls.2023.1285616. eCollection 2023. ABSTRACT INTRODUCTION: Ainaxiang (Blumea balsamifera (Linn.) DC.) is cultivated for the extraction of (-)-borneol and...
Polysubstance Use Profiles and HIV Viremia in a South African Cohort of Female Sex Workers: A Latent Class Analysis
J Acquir Immune Defic Syndr. 2023 Nov 30. doi: 10.1097/QAI.0000000000003356. Online ahead of print. ABSTRACT BACKGROUND: Given intersecting social and structural factors, female sex workers...
The role of sex in daily levels of high-risk alcohol and cannabis co-use
Drug Alcohol Depend Rep. 2023 Oct 31;9:100203. doi: 10.1016/j.dadr.2023.100203. eCollection 2023 Dec. ABSTRACT BACKGROUND: Co-use of alcohol and cannabis is highly prevalent and may be...
Perceived Risks and Therapeutic Benefits of Cannabis Among College Students Amidst the COVID-19 Pandemic
Cannabis. 2023 Nov 3;6(3):18-33. doi: 10.26828/cannabis/2023/000157. eCollection 2023. ABSTRACT More than half of the United States has legalized medicinal and/or recreational cannabis. The purpose of...
Interaction of endocannabinoid system and cyclooxygenase metabolites with fatty acid amide hydrolase and cyclooxygenase enzyme activities on contractile responses in rat vas deferens tissue
Naunyn Schmiedebergs Arch Pharmacol. 2023 Nov 30. doi: 10.1007/s00210-023-02861-3. Online ahead of print. ABSTRACT The endocannabinoid system and prostaglandins are important modulators in the genitourinary...
n-3 PUFAs synergistically enhance the efficacy of doxorubicin by inhibiting the proliferation and invasion of breast cancer cells
Med Oncol. 2023 Nov 28;41(1):2. doi: 10.1007/s12032-023-02229-w. ABSTRACT Breast cancer stands as a prominent contributor to cancer-related fatalities among women globally, characterized by an unfavorable...
Correlation between immune-related Tryptophan-Kynurenine pathway and severity of severe pneumonia and inflammation-related polyunsaturated fatty acids
Immun Inflamm Dis. 2023 Nov;11(11):e1088. doi: 10.1002/iid3.1088. ABSTRACT BACKGROUND: Immune dysfunction and oxidative stress caused by severe pneumonia can lead to multiple organ dysfunction and...
Cannabis and pathologies in dogs and cats: first survey of phytocannabinoid use in veterinary medicine in Argentina
J Cannabis Res. 2023 Nov 29;5(1):39. doi: 10.1186/s42238-023-00209-5. ABSTRACT BACKGROUND: In animals, the endocannabinoid system regulates multiple physiological functions. Like humans, animals respond to preparations...