The Quantity and Quality of Flax and Hemp Fibers Obtained Using the Osmotic, Water-, and Dew-Retting Processes
Materials (Basel). 2023 Nov 29;16(23):7436. doi: 10.3390/ma16237436. ABSTRACT This study presents the quantity and quality of flax (Linum usitatissimum L.) and hemp (Cannabis sativa L.)...
The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer’s Disease
J Clin Med. 2023 Nov 21;12(23):7201. doi: 10.3390/jcm12237201. ABSTRACT Alzheimer’s disease (AD) is characterized by massive neuronal death, brain atrophy, and loss of neurons and...
In Vitro and In Vivo Anti-Inflammatory Potential of Cannabichromene Isolated from Hemp
Plants (Basel). 2023 Nov 25;12(23):3966. doi: 10.3390/plants12233966. ABSTRACT Cannabichromene (CBC), a non-psychoactive cannabinoid found in Cannabis sativa, has recently been shown to possess several medicinal...
Metallothionein Family Proteins as Regulators of Zinc Ions Synergistically Enhance the Anticancer Effect of Cannabidiol in Human Colorectal Cancer Cells
Int J Mol Sci. 2023 Nov 22;24(23):16621. doi: 10.3390/ijms242316621. ABSTRACT Cannabidiol (CBD) is a chemical obtained from Cannabis sativa; it has therapeutic effects on anxiety...
Bioengineering of the Marine Diatom Phaeodactylum tricornutum with Cannabis Genes Enables the Production of the Cannabinoid Precursor, Olivetolic Acid
Int J Mol Sci. 2023 Nov 22;24(23):16624. doi: 10.3390/ijms242316624. ABSTRACT The increasing demand for novel natural compounds has prompted the exploration of innovative approaches in...
Neuroprotection and Beyond: The Central Role of CB1 and CB2 Receptors in Stroke Recovery
Int J Mol Sci. 2023 Nov 24;24(23):16728. doi: 10.3390/ijms242316728. ABSTRACT The endocannabinoid system, with its intricate presence in numerous cells, tissues, and organs, offers a...
Molecular Changes Associated with Suicide
Int J Mol Sci. 2023 Nov 24;24(23):16726. doi: 10.3390/ijms242316726. ABSTRACT Suicide is a serious global public health problem, with a worrying recent increase in suicide...
Characterizing cannabis-prevalent terpenes for neuroprotection reveal a role for α and β-pinenes in mitigating amyloid β-evoked neurotoxicity and aggregation in vitro
Neurotoxicology. 2023 Dec 7;100:16-24. doi: 10.1016/j.neuro.2023.12.004. Online ahead of print. ABSTRACT BACKGROUND: Cannabis sativa L. (C. sativa) can efficiently synthesize of over 200 terpenes, including...
Comorbid substance use disorder, major depression, and associated disability in a nationally representative sample
J Affect Disord. 2023 Dec 7:S0165-0327(23)01483-0. doi: 10.1016/j.jad.2023.12.016. Online ahead of print. ABSTRACT BACKGROUND: Major depression episodes (MDE) and substance use disorders (SUDs) are commonly...
Prevalence and correlates of past 30-day dual-vaping of nicotine and cannabis among adolescents in five New England states
Drug Alcohol Depend. 2023 Dec 6;254:111055. doi: 10.1016/j.drugalcdep.2023.111055. Online ahead of print. ABSTRACT SIGNIFICANCE: Adolescent vaping behavior includes vaping of multiple substances, including both nicotine...
Impact of non-medical cannabis legalization with market restrictions on health service use and incident cases of psychotic disorder in Ontario, Canada
Int J Drug Policy. 2023 Dec 9;123:104285. doi: 10.1016/j.drugpo.2023.104285. Online ahead of print. ABSTRACT BACKGROUND: Cannabis is a risk factor in the onset and persistence...
Assessing the risk of COVID-19 reinfection and severe outcomes among individuals with substance use disorders: a retrospective study using real-world electronic health records
BMJ Open. 2023 Dec 10;13(12):e074993. doi: 10.1136/bmjopen-2023-074993. ABSTRACT OBJECTIVE: Despite advancement in vaccines and treatments for COVID-19 over the past 2 years, many concerns remain...
A quantitative pharmacology model for cannabinoid receptor type 1 (CB1 ) mediated by Gi/Gs protein competition
Br J Pharmacol. 2023 Dec 10. doi: 10.1111/bph.16293. Online ahead of print. ABSTRACT BACKGROUND AND PURPOSE: Orthosteric agonism of the CB1 receptor normally associates with...
A cross-sectional study of correlations among blood-based biomarkers for intestinal permeability: A pilot study of United States veterans with posttraumatic stress disorder symptoms
Brain Behav Immun Health. 2023 Nov 10;34:100702. doi: 10.1016/j.bbih.2023.100702. eCollection 2023 Dec. ABSTRACT While many studies of intestinal permeability (IP) are focused on those with...
Cannabinoids and the endocannabinoid system in immunotherapy: helpful or harmful?
Front Oncol. 2023 Nov 22;13:1296906. doi: 10.3389/fonc.2023.1296906. eCollection 2023. ABSTRACT Numerous studies in various cancer models have demonstrated that ingredients of cannabis can influence tumor...