Determination of four amide synthetic cannabinoid isomers by ultra-high performance liquid chromatography-high resolution mass spectrometry
Se Pu. 2024 Jan 8;42(1):84-91. doi: 10.3724/SP.J.1123.2023.07007. ABSTRACT Isomerization commonly occurs in synthetic cannabinoids (SCs). Owing to the few differences in their structure and properties,...
Reported exposures to derived cannabis products in California before and after the 2018 federal reclassification of hemp
Int J Drug Policy. 2024 Jan 8;124:104313. doi: 10.1016/j.drugpo.2023.104313. Online ahead of print. ABSTRACT BACKGROUND: As of June 2023, a majority of states had legalized...
β-Caryophyllene inhibits monoacylglycerol lipase activity and increases 2-arachidonoyl glycerol levels in vivo: a new mechanism of endocannabinoid-mediated analgesia?
Mol Pharmacol. 2024 Jan 9:MOLPHARM-AR-2023-000668. doi: 10.1124/molpharm.123.000668. Online ahead of print. ABSTRACT Introduction. The mechanisms of BCP-induced analgesia are not well studied. Here, we tested...
Unmet Healthcare Needs and Medical Cannabis Use Among Sexual and Gender Minoritized Adults in a High-Stigma Environment
J Homosex. 2024 Jan 9:1-19. doi: 10.1080/00918369.2024.2302427. Online ahead of print. ABSTRACT Sexual and gender minoritized (SGM) individuals in high-stigma areas may use cannabis to...
Fungal enzyme degradation of lignin-PLA composites: Insights from experiments and molecular docking simulations
Heliyon. 2023 Dec 17;10(1):e23838. doi: 10.1016/j.heliyon.2023.e23838. eCollection 2024 Jan 15. ABSTRACT Fungal enzymes are effective in degrading various polymeric materials. In this study, we assessed...
The NLRP3 inflammasome: a vital player in inflammation and mediating the anti-inflammatory effect of CBD
Inflamm Res. 2024 Jan 8. doi: 10.1007/s00011-023-01831-y. Online ahead of print. ABSTRACT BACKGROUND: The NLRP3 inflammasome is a vital player in the emergence of inflammation....
Individuals’ Values and Preferences Regarding Medical Cannabis for Chronic Pain: A Descriptive Qualitative Study
J Pain Res. 2024 Jan 3;17:21-34. doi: 10.2147/JPR.S432823. eCollection 2024. ABSTRACT BACKGROUND: Cannabis for medical purposes has been legal in Canada since 2001; however, physicians...
Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims
Front Pharmacol. 2023 Dec 14;14:1273540. doi: 10.3389/fphar.2023.1273540. eCollection 2023. ABSTRACT Introduction: The unmet need for highly effective, naturally derived products with minimal side effects results...
Contractility of isolated colonic smooth muscle strips from rats treated with cancer chemotherapy: differential effects of cisplatin and vincristine
Front Neurosci. 2023 Dec 18;17:1304609. doi: 10.3389/fnins.2023.1304609. eCollection 2023. ABSTRACT BACKGROUND: Certain antineoplastic drugs cause gastrointestinal disorders even after the end of treatment. Enteric neuropathy...
Trema orientale (L.) Blume: A review of its taxonomy, traditional uses, phytochemistry, pharmacological activities and domestication potential
Heliyon. 2023 Dec 13;10(1):e23640. doi: 10.1016/j.heliyon.2023.e23640. eCollection 2024 Jan 15. ABSTRACT Trema orientale (L.) Blume is an important medicinal plant with multiple applications for treating...
Cerebrovascular Events and Hospital Discharge Outcomes Associated With Drug Use: A Retrospective Case-Matched Study
Cureus. 2023 Dec 8;15(12):e50190. doi: 10.7759/cureus.50190. eCollection 2023 Dec. ABSTRACT Introduction Individuals using cocaine, methamphetamines, cannabis, and other mood-altering drugs (MADs) have been reported to...
Sesquiterpene-evoked phytochemical toxicity in PC12 neuronal cells reveals a variable degree of oxidative stress and alpha-tocopherol and glutathione-dependent protection
Curr Res Toxicol. 2023 Dec 16;6:100144. doi: 10.1016/j.crtox.2023.100144. eCollection 2024. ABSTRACT Phytochemicals are often promoted generally as antioxidants and demonstrate variable levels of reactive oxygen...
The analysis of classical, polynomial regression and cubic spline mathematical models in hemp biodiesel optimization: an experimental comparison
Environ Sci Pollut Res Int. 2024 Jan 8. doi: 10.1007/s11356-023-31720-0. Online ahead of print. ABSTRACT Post-pandemic inflationist pressures, climate changes and extremes, regional conflicts, and...
Effect of dietary interventions on markers of type 2 inflammation in asthma: A systematic review
Respir Med. 2024 Jan;221:107504. doi: 10.1016/j.rmed.2023.107504. Epub 2023 Dec 22. ABSTRACT INTRODUCTION: Type 2 (T2) inflammation is a key mechanism in the pathophysiology of asthma....
Climate-based variability in the essential fatty acid composition of soybean oil
Am J Clin Nutr. 2024 Jan;119(1):58-68. doi: 10.1016/j.ajcnut.2023.08.024. Epub 2023 Nov 30. ABSTRACT BACKGROUND: Soybean oil is a major dietary source of the essential fatty...