Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients

Lipids Health Dis. 2022 Mar 25;21(1):31. doi: 10.1186/s12944-022-01642-w.

ABSTRACT

Omega 3 polyunsaturated fatty acids (n-3 PUFA) are known to have beneficial effects on cardiovascular and metabolic health. However, whether different sources of n-3 PUFA, for instance fatty fish vs vegetable oils, could elicit different effects on glucose and lipid metabolism, remains to be determined. Herein we examine recent findings showing that while a plant-based n-3 PUFA supplementation for six months can reduce fasting blood glucose, marine-based n-3 PUFA can instead reduce serum levels of triglycerides. We also discuss the potential molecular mechanisms that could underlie these different effects on the regulation of glycolipid metabolism.

PMID:35337345 | PMC:PMC8957175 | DOI:10.1186/s12944-022-01642-w