HomeIngredientMultifactor assessments to determine the overall performance of supercritical fluid extraction from Gynura procumbens essential oil

Multifactor assessments to determine the overall performance of supercritical fluid extraction from Gynura procumbens essential oil

October 23, 2022

Sci Rep. 2022 Aug 22;12(1):14293. doi: 10.1038/s41598-022-16773-4.

ABSTRACT

Gynura procumbens is a medicinal herb that contains bioactive compounds that can relieve coughs and prevent liver cancer. Supercritical fluid extraction (SFE) was suggested as one of the techniques that can be used to extract the valuable compounds from the G. procumbens. SFE was widely applied in extracting medicinal ingredients from herbs. However, most of them were performed only at the laboratory scale. Moreover, study to increase the yield performance, economic studies and safety assessments of the SFE process were also performed; however, these tests were conducted individually. Moreover, to date, there is no integration study between all the factors stated for determining the overall performance of SFE with herbs specifically G. procumbens. The integration between all the factors is beneficial because the data on the overall performance can assist in developing the SFE process with G. procumbens at the pilot or industrial scale. Therefore, this study incorporated a multifactor approach to measure the overall performance of the SFE process towards G. procumbens by using a rating and index approach. A summary of factors, such as the solubility of G. procumbens in CO2, operational cost and safety assessment elements, were taken into consideration as the main influences that determine the overall performance index of this study. Iperformance or overall performance of SFE from G. procumbens was successfully assessed and compared with response surface methodology (RSM). Overall, the results from Iperformance exhibit satisfactory solubility values when compared to the optimized value from RSM when considering the lowest operational costs in the safest SFE environment.

PMID:35995970 | PMC:PMC9395385 | DOI:10.1038/s41598-022-16773-4

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Patrick Blanchard MD

Meet Dr. Blanchard Dr. Blanchard’s medical practice is an embodiment of Integrative health which brings conventional and complementary approaches together in a coordinated way. Conveniently located in sunny Florida and over the internet with ValiseMD’s secure HIPPA compliant telXmed servers. Since 1994, patients with a wide range of challenging medical problems have achieved optimum health using the best of natural medicine, judiciously combined with high-tech innovations. Breakthroughs are often achieved even after patients have consulted mainstream specialists and holistic practitioners. Dr. Blanchard is founder and CEO of ValiseMD, Inc. He is board certified in Family Medicine since 1994 and awarded Fellow of the American Academy of Family Physicians in 2001. He received the ‘Teacher of the Year’ award from the University of Kansas School of Medicine at completion of his residency in Family Medicine. He completed a fellowship at Wake Forest University in the field of vascular neurosonology. He holds a medical patent in the field of Gastroenterology. He holds an unrestricted license to practice medicine and surgery in Florida. He started his medical career as a Emergency Medical Technician, then as a Paramedic and later a Medical Doctor.