Efficacy of a mixed preparation containing piperine, capsaicin and curcumin in the treatment of alopecia areata

J Cosmet Dermatol. 2022 Mar 23. doi: 10.1111/jocd.14931. Online ahead of print.

ABSTRACT

Alopecia areata is a common non-scarring alopecia, mainly manifested as sudden localized patchy alopecia. It is currently believed to be related to autoimmune, genetic, emotional stress and endocrine factors. 60 patients were enrolled in this study and divided into 2 groups randomly: topical treated with the mixed preparation (case) twice daily and minoxidil (control) once daily for 3 months. The degree of hair loss was assessed by SALT and dermoscopy . Based on our findings, the mixed preparation of piperine, capsaicin and curcumin is effective in treating alopecia areata, but it has not been shown to be superior to minoxidil in short-term therapy.

PMID:35318791 | DOI:10.1111/jocd.14931