Beyond Pain Relief: A Review on Cannabidiol Potential in Medical Therapies
Pharmaceuticals (Basel). 2023 Jan 20;16(2):155. doi: 10.3390/ph16020155. ABSTRACT The phytocannabinoid cannabidiol (CBD) is receiving increasing attention due to its pharmacological properties. Although CBD is extracted...
Dietary supplementation with n-3 polyunsaturated fatty acids: Effects on reproductive and productive performance and meat quality in rabbit breeding
Anim Nutr. 2023 Apr 25;14:70-78. doi: 10.1016/j.aninu.2023.03.009. eCollection 2023 Sep. ABSTRACT Rabbit breeding has many critical aspects related to reproduction, production, and animal welfare, which...
Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo
Front Synaptic Neurosci. 2023 May 12;15:1176864. doi: 10.3389/fnsyn.2023.1176864. eCollection 2023. ABSTRACT Cannabis exposure during gestation evokes significant molecular modifications to neurodevelopmental programs leading to neurophysiological...
Different Fatty Acid Supplementation in Low-Protein Diets Regulate Nutrient Utilization and Lipid and Amino Acid Metabolism in Weaned Pigs Model
Int J Mol Sci. 2023 May 9;24(10):8501. doi: 10.3390/ijms24108501. ABSTRACT This study was conducted to evaluate the effects of a low-protein (LP) diet supplemented with...
Cardioprotective mechanisms of cytochrome P450 derived oxylipins from ω-3 and ω-6 PUFAs
Adv Pharmacol. 2023;97:201-227. doi: 10.1016/bs.apha.2023.02.001. Epub 2023 Mar 27. ABSTRACT The seminal discovery that cytochrome P450 enzymes (CYPs) can oxidize polyunsaturated fatty acids (PUFAs) sparked...
DHA Supplementation During Pregnancy Enhances Maternal Vagally Mediated Cardiac Autonomic Control in Humans
J Nutr. 2022 Dec;152(12):2708-2715. doi: 10.1093/jn/nxac178. Epub 2023 Feb 10. ABSTRACT BACKGROUND: DHA is an essential omega-3 (ω-3; n-3) fatty acid that has well-established benefits...
Different Fatty Acid Supplementation in Low-Protein Diets Regulate Nutrient Utilization and Lipid and Amino Acid Metabolism in Weaned Pigs Model
Int J Mol Sci. 2023 May 9;24(10):8501. doi: 10.3390/ijms24108501. ABSTRACT This study was conducted to evaluate the effects of a low-protein (LP) diet supplemented with...
Omega-3 versus Omega-6: Are We Underestimating the Ecological Significance of Arachidonic Acid in Aquatic Systems?
Biomolecules. 2023 May 3;13(5):791. doi: 10.3390/biom13050791. ABSTRACT The long-chain polyunsaturated fatty acids (PUFA) eicosapentaenoic acid (EPA, ω-3, or n-3) and arachidonic acid (ARA, ω-6 or...
β-Glucan and Fatty Acid Based Mucoadhesive Carrier for Gastrointestinal Tract Specific Local and Sustained Drug Delivery
Biomolecules. 2023 Apr 28;13(5):768. doi: 10.3390/biom13050768. ABSTRACT The oral route is considered the most convenient route of drug administration for both systemic and local delivery....
Lipid mediators generated by the cytochrome P450-Epoxide hydrolase pathway
Adv Pharmacol. 2023;97:327-373. doi: 10.1016/bs.apha.2022.12.004. Epub 2023 Jan 19. ABSTRACT The cytochrome P450 (CYP) soluble epoxide hydrolase (sEH) pathway generates a large number of biologically...
Docosahexaenoic Acid Promotes Cd Excretion by Restoring the Abundance of Parabacteroides in Cd-Exposed Mice
Molecules. 2023 May 21;28(10):4217. doi: 10.3390/molecules28104217. ABSTRACT As a common harmful pollutant, cadmium (Cd) can easily enter the human body through the food chain, posing...
Characterization of the Nonpolar and Polar Extractable Components of Glanded Cottonseed for Its Valorization
Molecules. 2023 May 19;28(10):4181. doi: 10.3390/molecules28104181. ABSTRACT Cottonseed is the second major product of cotton (Gossypium spp.) crops after fiber. Thus, the characterization and valorization...
Characterization of a New Thermostable and Organic Solution-Tolerant Lipase from Pseudomonas fluorescens and Its Application in the Enrichment of Polyunsaturated Fatty Acids
Int J Mol Sci. 2023 May 18;24(10):8924. doi: 10.3390/ijms24108924. ABSTRACT The search for and characterization of new lipases with excellent properties has always been urgent...
Polyunsaturated Fatty Acids: Conversion to Lipid Mediators, Roles in Inflammatory Diseases and Dietary Sources
Int J Mol Sci. 2023 May 16;24(10):8838. doi: 10.3390/ijms24108838. ABSTRACT Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their role was...
Lipid Emulsion Inhibits Amlodipine-Induced Nitric Oxide-Mediated Vasodilation in Isolated Rat Aorta
Int J Mol Sci. 2023 May 14;24(10):8741. doi: 10.3390/ijms24108741. ABSTRACT This study aimed to examine the effect of lipid emulsion on the vasodilation induced by...