Cocoa Flavanols Improve Vascular Responses to Acute Mental Stress in Young Healthy Adults
Nutrients. 2021 Mar 27;13(4):1103. doi: 10.3390/nu13041103. ABSTRACT Mental stress has been shown to induce cardiovascular events, likely due to its negative impact on vascular function....
Acute Effects of Cocoa Flavanols on Blood Pressure and Peripheral Vascular Reactivity in Type 2 Diabetes Mellitus and Essential Hypertension: A Protocol for an Acute, Randomized, Double-Blinded, Placebo-Controlled Cross-Over Trial
Front Cardiovasc Med. 2021 Mar 15;8:602086. doi: 10.3389/fcvm.2021.602086. eCollection 2021. ABSTRACT Introduction: Patients with type 2 diabetes mellitus are at high risk to develop vascular...
Dietary flavanols improve cerebral cortical oxygenation and cognition in healthy adults
Sci Rep. 2020 Nov 24;10(1):19409. doi: 10.1038/s41598-020-76160-9. ABSTRACT Cocoa flavanols protect humans against vascular disease, as evidenced by improvements in peripheral endothelial function, likely through...
Preventive effect of cocoa flavanols against glucotoxicity-induced vascular inflammation in the arteria of diabetic rats and on the inflammatory process in TNF-alpha-stimulated endothelial cells
Food Chem Toxicol. 2020 Dec;146:111824. doi: 10.1016/j.fct.2020.111824. Epub 2020 Oct 21. ABSTRACT Hyperglycaemia induces a vascular inflammatory process that is a critical event in cardiovascular...
The Relationship Between Dietary Choices and Health and Premature Vascular Ageing
Heart Lung Circ. 2021 Nov;30(11):1647-1657. doi: 10.1016/j.hlc.2021.07.009. Epub 2021 Aug 12. ABSTRACT The paper aims to review the available data about the main mechanisms enabling...
An update on vinpocetine: New discoveries and clinical implications
Eur J Pharmacol. 2018 Jan 15;819:30-34. doi: 10.1016/j.ejphar.2017.11.041. Epub 2017 Nov 26. ABSTRACT Vinpocetine, a derivative of the alkaloid vincamine, has been clinically used in...
Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice
Neuroscience. 2015 Nov 12;308:180-93. doi: 10.1016/j.neuroscience.2015.09.005. Epub 2015 Sep 7. ABSTRACT Severe chronic stress can have a profoundly negative impact on the brain, affecting plasticity,...
Targets for the prevention of dementia
J Alzheimers Dis. 2010;20(3):915-24. doi: 10.3233/JAD-2010-091657. ABSTRACT The prevalence of dementia is expected to increase dramatically over the upcoming decades due to the aging population....
Self-Reported Omega-3 Supplement Use Moderates the Association between Age and Exercising Cerebral Blood Flow Velocity in Older Adults
Nutrients. 2020 Mar 5;12(3):697. doi: 10.3390/nu12030697. ABSTRACT Cerebral blood flow (CBF) decreases across the lifespan, and chronic conditions such as dementia and stroke accelerate this...
Red Yeast Rice Protects Circulating Bone Marrow-Derived Proangiogenic Cells against High-Glucose-Induced Senescence and Oxidative Stress: The Role of Heme Oxygenase-1
Oxid Med Cell Longev. 2017;2017:3831750. doi: 10.1155/2017/3831750. Epub 2017 May 6. ABSTRACT The inflammation and oxidative stress of bone marrow-derived proangiogenic cells (PACs), also named...
Effect of red yeast rice combined with antioxidants on lipid pattern, hs-CRP level, and endothelial function in moderately hypercholesterolemic subjects
Ther Clin Risk Manag. 2016 Feb 23;12:281-6. doi: 10.2147/TCRM.S91817. eCollection 2016. ABSTRACT Our aim was to test, through a crossover, double-blind, placebo-controlled randomized clinical trial,...
Cholesterol-Lowering Nutraceuticals Affecting Vascular Function and Cardiovascular Disease Risk
Curr Cardiol Rep. 2018 May 25;20(7):53. doi: 10.1007/s11886-018-0994-7. ABSTRACT PURPOSE OF REVIEW: The aim of this review is to provide an update on the effects...
Effects on oral fat load of a nutraceutical combination of fermented red rice, sterol esters and stanols, curcumin, and olive polyphenols: A randomized, placebo controlled trial
Phytomedicine. 2018 Mar 15;42:75-82. doi: 10.1016/j.phymed.2018.01.014. Epub 2018 Jan 31. ABSTRACT BACKGROUND: In literature, there are several studies about the effects of nutraceutical combinations at...
Red yeast rice, monacolin K, and pleiotropic effects.
Recenti Prog Med. 2018 Feb;109(2):154e-157e. doi: 10.1701/2865.28917. ABSTRACT The extracts of red yeast rice represent a nutraceutical with proven cholesterol lowering effect. Its efficacy is...
Acute and Long Term Effects of a Nutraceutical Combination on Lipid Profile, Glucose Metabolism and Vascular Function in Patients with Dyslipidaemia with and Without Cigarette Smoking
High Blood Press Cardiovasc Prev. 2021 Sep;28(5):483-491. doi: 10.1007/s40292-021-00468-4. Epub 2021 Sep 13. ABSTRACT INTRODUCTION: Lifestyle changes present a fundamental role in cardiovascular prevention. Nutraceuticals...