Dietary long-chain omega 3 fatty acids modify sphingolipid metabolism to facilitate airway hyperreactivity
Sci Rep. 2022 Nov 17;12(1):19735. doi: 10.1038/s41598-022-21083-w. ABSTRACT Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential nutrients that can affect inflammatory responses. While n-3 PUFAs...
Lactobacillus fermentum (MTCC-5898) based fermented whey renders prophylactic action against colitis by strengthening the gut barrier function and maintaining immune homeostasis
Microb Pathog. 2022 Nov 16:105887. doi: 10.1016/j.micpath.2022.105887. Online ahead of print. ABSTRACT Nutritional intervention using probiotic fermented dairy product has emerged as a promising prophylactic...
In vitro characterization of lactic acid bacterial strains isolated from fermented foods with anti-inflammatory and dipeptidyl peptidase-IV inhibition potential
Braz J Microbiol. 2022 Nov 18. doi: 10.1007/s42770-022-00872-5. Online ahead of print. ABSTRACT Probiotics are known to stimulate, modulate, and regulate host immune response by...
Susceptibility to milk fat depression in dairy sheep and goats: Individual variation in ruminal fermentation and biohydrogenation
J Dairy Sci. 2022 Nov 15:S0022-0302(22)00659-2. doi: 10.3168/jds.2022-22248. Online ahead of print. ABSTRACT Small ruminants are susceptible to milk fat depression (MFD) induced by marine...
Myrrhone inhibits the progression of hepatic fibrosis by regulating the abnormal activation of hepatic stellate cells
J Biochem Mol Toxicol. 2022 Nov;36(11):e23177. doi: 10.1002/jbt.23177. Epub 2022 Aug 19. ABSTRACT We focus on exploring the antihepatic fibrosis effect of Myrrhone (Myr), a...
Effects of aromatherapy on fatigue, quality of sleep and quality of life in patients with inflammatory bowel disease: A feasibility study
Complement Ther Clin Pract. 2022 Nov;49:101648. doi: 10.1016/j.ctcp.2022.101648. Epub 2022 Aug 2. ABSTRACT BACKGROUND: Fatigue, poor sleep quality and poor quality of life (QoL) are...
Dry Eye Subtypes in the Dry Eye Assessment and Management (DREAM) Study: A Latent Profile Analysis
Transl Vis Sci Technol. 2022 Nov 1;11(11):13. doi: 10.1167/tvst.11.11.13. ABSTRACT PURPOSE: Dry eye disease (DED) is a heterogeneous condition with poorly characterized subtypes. The DREAM...
Decreased Levels of Erythrocyte Membrane Arachidonic and Docosahexaenoic Acids Are Associated With Retinopathy of Prematurity
Invest Ophthalmol Vis Sci. 2022 Nov 1;63(12):23. doi: 10.1167/iovs.63.12.23. ABSTRACT PURPOSE: Retinopathy of prematurity (ROP) can lead to blindness. Arachidonic acid (ARA) and docosahexaenoic acid...
Efficacy of newly developed kombucha-based specialized food product for treatment of constipation-predominant irritable bowel syndrome
Vopr Pitan. 2022;91(5):95-104. doi: 10.33029/0042-8833-2022-91-5-95-104. Epub 2022 Aug 30. ABSTRACT According to studies, the prevalence of constipation in the population can reach 27% due to...
Models predict change in plasma triglyceride concentrations and long-chain n-3 polyunsaturated fatty acid proportions in healthy participants after fish oil intervention
Front Nutr. 2022 Oct 25;9:989716. doi: 10.3389/fnut.2022.989716. eCollection 2022. ABSTRACT INTRODUCTION: Substantial response heterogeneity is commonly seen in dietary intervention trials. In larger datasets, this...
Chronically administered Agave americana var. marginata extract ameliorates diabetes mellitus, associated behavioral comorbidities and biochemical parameters in alloxan-induced diabetic rats
Saudi Pharm J. 2022 Oct;30(10):1373-1386. doi: 10.1016/j.jsps.2022.06.003. Epub 2022 Jun 13. ABSTRACT INTRODUCTION: Diabetes mellitus causes hyperglycemia and associated complications to the brain. In current...
Single melatonin injection enhances the testicular artery hemodynamic, reproductive hormones, and semen parameters in German shepherd dogs
BMC Vet Res. 2022 Nov 14;18(1):403. doi: 10.1186/s12917-022-03487-y. ABSTRACT This study aimed to determine the effects of melatonin administration on testicular vascular perfusion in relation...
Study protocol of the PROUD48 study comparing the effects of pemafibrate and omega-3 fatty acid ethyl esters on ApoB-48 in statin-treated patients with dyslipidaemia: a prospective, multicentre, open-label, randomised, parallel group trial in Japan
BMJ Open. 2022 Nov 14;12(11):e061360. doi: 10.1136/bmjopen-2022-061360. ABSTRACT INTRODUCTION: This study will compare the lowering effects of pemafibrate and omega-3 fatty acid ethyl esters on...
Acute and long-term exercise differently modulate plasma levels of oxylipins, endocannabinoids, and their analogues in young sedentary adults: A sub-study and secondary analyses from the ACTIBATE randomized controlled-trial
EBioMedicine. 2022 Nov;85:104313. doi: 10.1016/j.ebiom.2022.104313. Epub 2022 Oct 27. ABSTRACT BACKGROUND: Fatty acid-derived lipid mediators including oxylipins, endocannabinoids (eCBs), and their analogues, have emerged as...
Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis
FASEB J. 2022 Dec;36(12):e22648. doi: 10.1096/fj.202200982R. ABSTRACT Cyp4f18 catalyzes the conversion of n-3 polyunsaturated fatty acids (PUFAs) into omega-3 epoxides, such as 17,18-epoxyeicosatetraenoic acid (17,18-EpETE)...