A Natural Dietary Supplement with a Combination of Nutrients Prevents Neurodegeneration Induced by a High Fat Diet in Mice
Nutrients. 2018 Aug 21;10(9):1130. doi: 10.3390/nu10091130. ABSTRACT Obesity and metabolic disorders can be risk factors for the onset and development of neurodegenerative diseases. The aim...
Comprehensive metabolite profiling in distinct chemotypes of Commiphora wightii
Nat Prod Res. 2019 Jan;33(1):17-23. doi: 10.1080/14786419.2018.1431629. Epub 2018 Feb 2. ABSTRACT Commiphora wightii (Arn.) Bhandari, known as guggul, produces a medicinally important gum resin...
NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet
Nutrients. 2017 May 13;9(5):492. doi: 10.3390/nu9050492. ABSTRACT Non-alcoholic fatty liver disease (NAFLD) confers an increased risk of cardiovascular diseases. NAFDL is associated with atherogenic dyslipidemia,...
Is it possible to decrease cholesterol levels with dietary supplements?
Rev Med Suisse. 2016 Mar 2;12(508):451-3. ABSTRACT Patients often use dietary supplements for cardiovascular prevention. An US study showed that 75% of patients with cardiovascular...
Effect of a Natural Supplement Containing Curcuma Longa, Guggul, and Chlorogenic Acid in Patients With Metabolic Syndrome
Angiology. 2015 Oct;66(9):856-61. doi: 10.1177/0003319714568792. Epub 2015 Jan 27. ABSTRACT The impact of a natural supplement (Kepar; Rikrea, Italy), containing several plant extracts such as...
Efficient One-Step Biocatalytic Multienzyme Cascade Strategy for Direct Conversion of Phytosterol to C-17-Hydroxylated Steroids
Appl Environ Microbiol. 2021 Nov 24;87(24):e0032121. doi: 10.1128/AEM.00321-21. Epub 2021 Sep 29. ABSTRACT Steroidal 17-carbonyl reduction is crucial to the production of natural bioactive steroid...
Phytosterols and Cardiovascular Disease
Curr Atheroscler Rep. 2021 Sep 1;23(11):68. doi: 10.1007/s11883-021-00964-x. ABSTRACT PURPOSE OF REVIEW: Coronary heart disease is the leading cause of mortality worldwide. Elevated blood cholesterol...
Amelioration of Chlorpyrifos-Induced Toxicity in Brassica juncea L. by Combination of 24-Epibrassinolide and Plant-Growth-Promoting Rhizobacteria
Biomolecules. 2021 Jun 12;11(6):877. doi: 10.3390/biom11060877. ABSTRACT Pervasive use of chlorpyrifos (CP), an organophosphorus pesticide, has been proven to be fatal for plant growth, especially...
Effects of phytosterol supplementation on growth performance, serum lipid, proinflammatory cytokines, intestinal morphology, and meat quality of white feather broilers
Poult Sci. 2021 Jul;100(7):101096. doi: 10.1016/j.psj.2021.101096. Epub 2021 Mar 12. ABSTRACT The aim of this study was to evaluate the effects of dietary phytosterol (PS)...
Sterol sulfate alleviates atherosclerosis via mediating hepatic cholesterol metabolism in ApoE-/- mice
Food Funct. 2021 Jun 8;12(11):4887-4896. doi: 10.1039/d0fo03266b. ABSTRACT Compared with terrestrial organisms, the sterols in sea cucumber exhibit a sulfate group at the C-3 position....
24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease
Mar Drugs. 2021 Mar 27;19(4):190. doi: 10.3390/md19040190. ABSTRACT We recently found that dietary supplementation with the seaweed Sargassum fusiforme, containing the preferential LXRβ-agonist 24(S)-saringosterol, prevented...
Severe Genotype, Pancreatic Insufficiency and Low Dose of Pancreatic Enzymes Associate with Abnormal Serum Sterol Profile in Cystic Fibrosis
Biomolecules. 2021 Feb 19;11(2):313. doi: 10.3390/biom11020313. ABSTRACT BACKGROUND: Several factors could lead to lipid disturbances observed in cystic fibrosis (CF). This study aimed to assess...
Effect of phytosterols on reducing low-density lipoprotein cholesterol in dogs
Domest Anim Endocrinol. 2021 Jul;76:106610. doi: 10.1016/j.domaniend.2021.106610. Epub 2021 Jan 27. ABSTRACT Hyperlipidemia is described as an increase in serum and/or plasma levels of triglycerides,...
Methodological flaws in meta-analysis of phytosterol supplementation and plasma lipoprotein(a) and free fatty acid (FFA) concentrations: A letter to the editor
Nutr Metab Cardiovasc Dis. 2021 Mar 10;31(3):979-980. doi: 10.1016/j.numecd.2020.12.027. Epub 2021 Jan 5. NO ABSTRACT PMID:33551251 | DOI:10.1016/j.numecd.2020.12.027...
Impaired cholesterol metabolism in the mouse model of cystic fibrosis. A preliminary study
PLoS One. 2021 Jan 7;16(1):e0245302. doi: 10.1371/journal.pone.0245302. eCollection 2021. ABSTRACT This study aims to investigate cholesterol metabolism in a mouse model with cystic fibrosis (CF)...