Screening and characterization of a GH78 alpha-l-rhamnosidase from Aspergillus terreus and its application in the bioconversion of icariin to icaritin with recombinant beta-glucosidase
Enzyme Microb Technol. 2021 Nov 10;153:109940. doi: 10.1016/j.enzmictec.2021.109940. Online ahead of print. ABSTRACT In this study, a GH78 α-L-rhamnosidase AtRha from Aspergillus terreus CCF3059 was...
Effect of the icariin on endothelial microparticles, endothelial progenitor cells, platelets, and erectile function in spontaneously hypertensive rats
Andrology. 2021 Nov 14. doi: 10.1111/andr.13127. Online ahead of print. ABSTRACT OBJECTIVES: To investigate the effect of icariin on endothelial microparticles, endothelial progenitor cells, platelets,...
The Anti-Inflammatory Effect of a Combination of Five Compounds From Five Chinese Herbal Medicines Used in the Treatment of COPD
Front Pharmacol. 2021 Oct 27;12:709702. doi: 10.3389/fphar.2021.709702. eCollection 2021. ABSTRACT Effective compound combination (ECC; i.e, 20-S-ginsenoside Rh1, astragaloside, icariin, nobiletin, and paeonol), derived from Chinese...
Icariin accelerates cartilage defect repair by promoting chondrogenic differentiation of BMSCs under conditions of oxygen-glucose deprivation
J Cell Mol Med. 2021 Dec 3. doi: 10.1111/jcmm.17073. Online ahead of print. ABSTRACT This study explored the role played by combined ICA and bone...
3D printing of alginate dialdehyde-gelatin (ADA-GEL) hydrogels incorporating phytotherapeutic icariin loaded mesoporous SiO(2)-CaO nanoparticles for bone tissue engineering
Mater Sci Eng C Mater Biol Appl. 2021 Dec;131:112470. doi: 10.1016/j.msec.2021.112470. Epub 2021 Oct 2. ABSTRACT 3D printing enables a better control over the microstructure...
Hypolipaemic nutraceutics: red yeast rice and Armolipid, berberine and bergamot
Ann Agric Environ Med. 2021 Mar 18;28(1):81-88. doi: 10.26444/aaem/130629. Epub 2020 Dec 2. ABSTRACT INTRODUCTION: Increased serum cholesterol levels constitute one of the main risk...
Doctor, Do You Know Red Yeast Rice?
Praxis (Bern 1994). 2021;110(4):207-220. doi: 10.1024/1661-8157/a003617. ABSTRACT Doctor, Do You Know Red Yeast Rice? Abstract. We present cases of patients with high total cholesterol who...
Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial
Asia Pac J Clin Nutr. 2021 Sep;30(3):424-435. doi: 10.6133/apjcn.202109_30(3).0009. ABSTRACT BACKGROUND AND OBJECTIVES: Red yeast rice contains monacolin K, an inhibitor of cholesterol synthesis, and...
Nutraceutical Combinations in Hypercholesterolemia: Evidence from Randomized, Placebo-Controlled Clinical Trials
Nutrients. 2021 Sep 8;13(9):3128. doi: 10.3390/nu13093128. ABSTRACT There is an increasing number of nutraceutical combinations (NCs) on the market for hypercholesterolemia, although clinical trials to...
Acute and Long Term Effects of a Nutraceutical Combination on Lipid Profile, Glucose Metabolism and Vascular Function in Patients with Dyslipidaemia with and Without Cigarette Smoking
High Blood Press Cardiovasc Prev. 2021 Sep;28(5):483-491. doi: 10.1007/s40292-021-00468-4. Epub 2021 Sep 13. ABSTRACT INTRODUCTION: Lifestyle changes present a fundamental role in cardiovascular prevention. Nutraceuticals...
Nutraceuticals in the Management of Dyslipidemia: Which, When, and for Whom? Could Nutraceuticals Help Low-Risk Individuals with Non-optimal Lipid Levels?
Curr Atheroscler Rep. 2021 Aug 4;23(10):57. doi: 10.1007/s11883-021-00955-y. ABSTRACT PURPOSE OF REVIEW: The aim of this review is to summarize the available clinical efficacy and...
Postmarketing nutrivigilance safety profile: a line of dietary food supplements containing red yeast rice for dyslipidemia
Arch Med Sci. 2021 Mar 4;17(4):856-863. doi: 10.5114/aoms/133716. eCollection 2021. ABSTRACT INTRODUCTION: In the absence of a European standardized postmarketing food supplement surveillance system (nutrivigilance),...
Impact of nutraceuticals on markers of systemic inflammation: Potential relevance to cardiovascular diseases – A position paper from the International Lipid Expert Panel (ILEP)
Prog Cardiovasc Dis. 2021 Jul-Aug;67:40-52. doi: 10.1016/j.pcad.2021.06.010. Epub 2021 Jun 27. ABSTRACT Inflammation is a marker of arterial disease stemming from cholesterol-dependent to -independent molecular...
Lipid Profile and Vascular Remodelling in Young Dyslipidemic Subjects Treated with Nutraceuticals Derived from Red Yeast Rice
Cardiovasc Ther. 2021 Apr 22;2021:5546800. doi: 10.1155/2021/5546800. eCollection 2021. ABSTRACT BACKGROUND AND AIMS: A relevant role is emerging for functional foods in cardiovascular prevention. The...
A Combination of Lactoplantibacillus plantarum Strains CECT7527, CECT7528, and CECT7529 Plus Monacolin K Reduces Blood Cholesterol: Results from a Randomized, Double-Blind, Placebo-Controlled Study
Nutrients. 2021 Apr 6;13(4):1206. doi: 10.3390/nu13041206. ABSTRACT BACKGROUND: Dietary supplements have been proposed to help manage blood cholesterol, including red yeast rice (RYR) extracts, plant...