Impact of nutraceuticals on markers of systemic inflammation: Potential relevance to cardiovascular diseases – A position paper from the International Lipid Expert Panel (ILEP)
Prog Cardiovasc Dis. 2021 Jul-Aug;67:40-52. doi: 10.1016/j.pcad.2021.06.010. Epub 2021 Jun 27. ABSTRACT Inflammation is a marker of arterial disease stemming from cholesterol-dependent to -independent molecular...
Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial
Asia Pac J Clin Nutr. 2021 Sep;30(3):424-435. doi: 10.6133/apjcn.202109_30(3).0009. ABSTRACT BACKGROUND AND OBJECTIVES: Red yeast rice contains monacolin K, an inhibitor of cholesterol synthesis, and...
Nutraceutical Combinations in Hypercholesterolemia: Evidence from Randomized, Placebo-Controlled Clinical Trials
Nutrients. 2021 Sep 8;13(9):3128. doi: 10.3390/nu13093128. ABSTRACT There is an increasing number of nutraceutical combinations (NCs) on the market for hypercholesterolemia, although clinical trials to...
Effects of Supplementation with Folic Acid and Its Combinations with Other Nutrients on Cognitive Impairment and Alzheimer’s Disease: A Narrative Review
Nutrients. 2021 Aug 26;13(9):2966. doi: 10.3390/nu13092966. ABSTRACT Cognitive impairment and Alzheimer’s Disease, among other cognitive dysfunctions, has been recognized as a major public health problem....
Contrasting Metabolic Insufficiency in Aging and Dementia
Aging Dis. 2021 Jul 1;12(4):1081-1096. doi: 10.14336/AD.2021.0104. eCollection 2021 Jul. ABSTRACT Metabolic insufficiency and neuronal dysfunction occur in normal aging but is exaggerated in dementia...
Migraine and Vascular Risk: An Update
Neurol India. 2021 Mar-Apr;69(Supplement):S83-S90. doi: 10.4103/0028-3886.315974. ABSTRACT BACKGROUND: Migraine is a common neurological disorder with significant morbidity and disability. There is growing evidence that migraine...
Association Between Homocysteine and Vitamin Levels in Demented Patients
J Alzheimers Dis. 2021;81(4):1781-1792. doi: 10.3233/JAD-201481. ABSTRACT BACKGROUND: Although it is known that the nutritional status among elderly persons and, in particular, patients with dementia,...
Ubiquinol Supplementation Improves Gender-Dependent Cerebral Vasoreactivity and Ameliorates Chronic Inflammation and Endothelial Dysfunction in Patients with Mild Cognitive Impairment
Antioxidants (Basel). 2021 Jan 20;10(2):143. doi: 10.3390/antiox10020143. ABSTRACT Ubiquinol can protect endothelial cells from multiple mechanisms that cause endothelial damage and vascular dysfunction, thus contributing...
Safety of water extract of Cistanche tubulosa stems as a Novel food pursuant to Regulation (EU) 2015/2283
EFSA J. 2021 Jan 15;19(1):e06346. doi: 10.2903/j.efsa.2021.6346. eCollection 2021 Jan. ABSTRACT Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods...
Plasma Vitamin B12 Levels, High-Dose Vitamin B12 Treatment, and Risk of Dementia
J Alzheimers Dis. 2021;79(4):1601-1612. doi: 10.3233/JAD-201096. ABSTRACT BACKGROUND: It is controversial whether B12 deficiency causes dementia or B12 treatment can prevent dementia. OBJECTIVE: To assess...
Hydrogen sulfide attenuates hyperhomocysteinemia-induced blood-brain barrier permeability by inhibiting MMP-9
Int J Neurosci. 2021 Feb 1:1-11. doi: 10.1080/00207454.2020.1860967. Online ahead of print. ABSTRACT Backgroud: Hyperhomocysteinemia (HHcy) is implicated in various neurovascular disorders including vascular dementia,...
Lack of direct involvement of a diazepam long-term treatment in the occurrence of irreversible cognitive impairment: a pre-clinical approach
Transl Psychiatry. 2021 Dec 3;11(1):612. doi: 10.1038/s41398-021-01718-8. ABSTRACT Several observational studies have found a link between the long-term use of benzodiazepines and dementia, which remains...
Traumatic brain injuries among veterans and the risk of incident dementia: A systematic review & meta-analysis
Age Ageing. 2021 Oct 13:afab194. doi: 10.1093/ageing/afab194. Online ahead of print. ABSTRACT BACKGROUND: Traumatic brain injuries (TBI) among military veterans are increasingly recognized as important...
Is Organic Food Better For You?
Americans are embracing organics like never before. Once scant on supermarket shelves, organic foods have gained coveted space alongside their conventional food counterparts, whether produce,...
Ultrashort Peptides and Hyaluronic Acid-Based Injectable Composite Hydrogels for Sustained Drug Release and Chronic Diabetic Wound Healing
ACS Appl Mater Interfaces. 2021 Dec 3. doi: 10.1021/acsami.1c16738. Online ahead of print. ABSTRACT Peptide hydrogels are widely used for biomedical applications owing to their...