ACR Appropriateness Criteria Dementia
J Am Coll Radiol. 2020 May;17(5S):S100-S112. doi: 10.1016/j.jacr.2020.01.040. ABSTRACT Degenerative disease of the central nervous system is a growing public health concern. The primary role...
Self-Reported Omega-3 Supplement Use Moderates the Association between Age and Exercising Cerebral Blood Flow Velocity in Older Adults
Nutrients. 2020 Mar 5;12(3):697. doi: 10.3390/nu12030697. ABSTRACT Cerebral blood flow (CBF) decreases across the lifespan, and chronic conditions such as dementia and stroke accelerate this...
Angiopoietin-1 and alphanubeta3 integrin peptide promote the therapeutic effects of L-serine in an amyotrophic lateral sclerosis/Parkinsonism dementia complex model
Aging (Albany NY). 2018 Nov 25;10(11):3507-3527. doi: 10.18632/aging.101661. ABSTRACT Amyotrophic lateral sclerosis (ALS) is an adult disorder of neurodegeneration that manifests as the destruction of...
Berberine suppresses the ectopic expression of miR-133a in endothelial cells to improve vascular dementia in diabetic rats
Clin Exp Hypertens. 2019;41(8):708-716. doi: 10.1080/10641963.2018.1545846. Epub 2018 Nov 26. ABSTRACT Objective: Vascular dementia is the second leading cause of dementia, which is strongly associated...
Prolonged exposure to 1,25(OH)2D3 and high ionized calcium induces FGF-23 production in intestinal epithelium-like Caco-2 monolayer: A local negative feedback for preventing excessive calcium transport
Arch Biochem Biophys. 2018 Feb 15;640:10-16. doi: 10.1016/j.abb.2017.12.022. Epub 2018 Jan 6. ABSTRACT Overdose of oral calcium supplement and excessive intestinal calcium absorption can contribute...
Contrasting Metabolic Insufficiency in Aging and Dementia
Aging Dis. 2021 Jul 1;12(4):1081-1096. doi: 10.14336/AD.2021.0104. eCollection 2021 Jul. ABSTRACT Metabolic insufficiency and neuronal dysfunction occur in normal aging but is exaggerated in dementia...
Safety of water extract of Cistanche tubulosa stems as a Novel food pursuant to Regulation (EU) 2015/2283
EFSA J. 2021 Jan 15;19(1):e06346. doi: 10.2903/j.efsa.2021.6346. eCollection 2021 Jan. ABSTRACT Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods...
Cocoa Flavanols Protect Human Endothelial Cells from Oxidative Stress
Plant Foods Hum Nutr. 2020 Jun;75(2):161-168. doi: 10.1007/s11130-020-00807-1. ABSTRACT Oxidative stress may cause functional disorders of vascular endothelia which can lead to endothelial apoptosis and...
Chronic and acute effects of cocoa products intake on arterial stiffness and platelet count and function: A systematic review and dose-response Meta-analysis of randomized clinical trials
Crit Rev Food Sci Nutr. 2021;61(3):357-379. doi: 10.1080/10408398.2020.1733484. Epub 2020 Mar 4. ABSTRACT The findings of trials investigating the effect of cocoa products consumption on...
Acute (-)-Epicatechin Consumption: Effects on Local Vasodilation Following Resistance Exercise and High-Intensity Exercise Performance
Sports (Basel). 2020 Feb 15;8(2):22. doi: 10.3390/sports8020022. ABSTRACT (-)-Epicatechin is a polyphenol previously shown to enhance vascular health. The purposes of the current studies were...
The role of nutraceuticals in prevention and treatment of hypertension: An updated review of the literature
Food Res Int. 2020 Feb;128:108749. doi: 10.1016/j.foodres.2019.108749. Epub 2019 Nov 7. ABSTRACT Hypertension (HTN) is a worldwide epidemic in both developed and developing countries. It...
Chocolate, “Food of the Gods”: History, Science, and Human Health
Int J Environ Res Public Health. 2019 Dec 6;16(24):4960. doi: 10.3390/ijerph16244960. ABSTRACT Chocolate is well known for its fine flavor, and its history began in...
Effects of Cocoa-Rich Chocolate on Blood Pressure, Cardiovascular Risk Factors, and Arterial Stiffness in Postmenopausal Women: A Randomized Clinical Trial
Nutrients. 2020 Jun 12;12(6):1758. doi: 10.3390/nu12061758. ABSTRACT This study aimed to evaluate the effects of the intake of 10 g of cocoa-rich chocolate on blood...
Chronic Consumption of Bovine Dairy Milk Attenuates Dietary Saturated Fatty Acid-Induced Blood-Brain Barrier Dysfunction
Front Nutr. 2020 May 6;7:58. doi: 10.3389/fnut.2020.00058. eCollection 2020. ABSTRACT Ingestion of Western-diets enriched in long chain saturated fatty acids (LCSFA) are associated with increased...
Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model
Biochem Biophys Res Commun. 2021 Sep 24;571:74-80. doi: 10.1016/j.bbrc.2021.07.051. Epub 2021 Jul 22. ABSTRACT Transient global cerebral ischemia (tGCI) is a cerebrovascular disorder characterized by...