Alpha-linolenic acid modulates systemic and adipose tissue-specific insulin sensitivity, inflammation, and the endocannabinoid system in dairy cows
Sci Rep. 2023 Mar 31;13(1):5280. doi: 10.1038/s41598-023-32433-7. ABSTRACT Metabolic disorders are often linked to alterations in insulin signaling. Omega-3 (n-3) fatty acids modulate immunometabolic responses;...
Rimonabant-Based Compounds Bearing Hydrophobic Amino Acid Derivatives as Cannabinoid Receptor Subtype 1 Ligands
ACS Med Chem Lett. 2023 Mar 9;14(4):479-486. doi: 10.1021/acsmedchemlett.3c00024. eCollection 2023 Apr 13. ABSTRACT In this study, 1H-pyrazole-3-carboxylic acids related to the cannabinoid type 1...
Impaired inhibition after delta-9-tetrahydrocannabinol in women not related to circulating estradiol levels
Pharmacol Biochem Behav. 2023 Mar 31;225:173547. doi: 10.1016/j.pbb.2023.173547. Online ahead of print. ABSTRACT Cannabis and its main psychoactive constituent, delta-9-tetrahydrocannabinol (THC), impair cognitive processes, including...
Associations between plasma inflammatory markers and psychotic disorder, depressive disorder and generalised anxiety disorder in early adulthood: A nested case-control study
Brain Behav Immun. 2023 Mar 31;111:90-100. doi: 10.1016/j.bbi.2023.03.025. Online ahead of print. ABSTRACT BACKGROUND: Low-grade inflammation may occur in association with several mental disorders of...
Can we predict the treatment doses of THC and CBD and does it matter?
Eur J Intern Med. 2023 Mar 30:S0953-6205(23)00100-0. doi: 10.1016/j.ejim.2023.03.028. Online ahead of print. ABSTRACT INTRODUCTION: Medical cannabis is an increasingly prevalent treatment for a wide...
Effects of Δ9-Tetrahydrocannabinol and the Aminoalkylindole K2/Spice Constituent JWH-073 on Cardiac Tissue and Mesenteric Vascular Reactivity
Cannabis Cannabinoid Res. 2023 Apr 3. doi: 10.1089/can.2022.0325. Online ahead of print. ABSTRACT Background: Although use of Cannabis sativa is not associated with serious adverse...
The Estrous Cycle Influences the Effects of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Inhibition in the Anxiety-Like Behavior in Rats
Cannabis Cannabinoid Res. 2023 Apr 3. doi: 10.1089/can.2022.0329. Online ahead of print. ABSTRACT Background: Sex differences in the response to the anxiety-related effects of cannabinoid...
“You Almost Feel Out of Touch [For Saying] … ‘Oh, and by the way, Stop Smoking.'” A Qualitative Exploration of Provider Perspectives About Discussing Tobacco and Cannabis Use With 18-24-Year-Old Young Adults With HIV
J Int Assoc Provid AIDS Care. 2023 Jan-Dec;22:23259582231163125. doi: 10.1177/23259582231163125. ABSTRACT Background: Youth with HIV (YWH) aged 18-24 are overburdened by tobacco, with half also...
Medical cannabis for pain management in patients undergoing chronic hemodialysis: randomized, double-blind, cross-over, feasibility study
Clin Kidney J. 2022 Dec 23;16(4):701-710. doi: 10.1093/ckj/sfac275. eCollection 2023 Apr. ABSTRACT BACKGROUND: Chronic pain is prevalent but difficult to treat in patients undergoing hemodialysis...
Cannabinoid receptors involved in descending inhibition on spinal seizure-like activity in the phrenic output
Biomed Res. 2023;44(2):41-49. doi: 10.2220/biomedres.44.41. ABSTRACT Seizure-like burst activities are induced by blockade of GABAA and/or glycine receptors in various spinal ventral roots of brainstem-spinal...
Determination of 11 Cannabinoids in Cannabis sativa L. by Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (LC-Q-TOF-MS)
Yakugaku Zasshi. 2023;143(4):411-418. doi: 10.1248/yakushi.22-00198. ABSTRACT Eleven major cannabinoids from each subdivided tissue of drug-type and fiber-type cannabis plants were determined by means of a...
Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study
Psychiatry Res. 2023 May;323:115184. doi: 10.1016/j.psychres.2023.115184. Epub 2023 Mar 28. ABSTRACT BACKGROUND: People with schizophrenia spectrum disorders (SSD) frequently present cognitive impairments. Here, we investigated...
Sexually Dimorphic Adolescent Trajectories of Prefrontal Endocannabinoid Synaptic Plasticity Equalize in Adulthood, Reflected by Endocannabinoid System Gene Expression
Cannabis Cannabinoid Res. 2023 Apr 4. doi: 10.1089/can.2022.0308. Online ahead of print. ABSTRACT Introduction: How sex influences prefrontal cortexes (PFCs) synaptic development through adolescence remains...
An analysis of cannabinoid hyperemesis syndrome Reddit posts and themes
Clin Toxicol (Phila). 2023 Apr 4:1-7. doi: 10.1080/15563650.2023.2183790. Online ahead of print. ABSTRACT INTRODUCTION: Reddit hosts a large active community of members dedicated to the...
Suspected Suicidal Cannabis Exposures Reported to US Poison Centers, 2009-2021
JAMA Netw Open. 2023 Apr 3;6(4):e239044. doi: 10.1001/jamanetworkopen.2023.9044. NO ABSTRACT PMID:37074718 | DOI:10.1001/jamanetworkopen.2023.9044...