Rooted in therapeutics: comprehensive analyses of Cannabis sativa root extracts reveals potent antioxidant, anti-inflammatory, and bactericidal properties
Front Pharmacol. 2024 Sep 16;15:1465136. doi: 10.3389/fphar.2024.1465136. eCollection 2024. ABSTRACT Following the legalization of recreational Cannabis in Canada in 2018, the associated waste, including Cannabis...
Repeated Administration of a Full-Spectrum Cannabidiol Product, Not a Cannabidiol Isolate, Reverses the Lipopolysaccharide-Induced Depressive-Like Behavior and Hypolocomotion in a Rat Model of Low-Grade Subchronic Inflammation
Cannabis Cannabinoid Res. 2024 Sep 30. doi: 10.1089/can.2024.0086. Online ahead of print. ABSTRACT Background: Mounting evidence suggests that the phytocannabinoid cannabidiol (CBD) holds promise as...
Molecular Targets of Minor Cannabinoids in Breast Cancer: In Silico and In Vitro Studies
Pharmaceuticals (Basel). 2024 Sep 21;17(9):1245. doi: 10.3390/ph17091245. ABSTRACT BACKGROUND: Breast cancer therapy has been facing remarkable changes. Classic treatments are now combined with other therapies...
Subthreshold Cannabidiol Potentiates Levetiracetam in the Kainic Acid Model of Temporal Lobe Epilepsy: A Pilot Study
Pharmaceuticals (Basel). 2024 Sep 10;17(9):1187. doi: 10.3390/ph17091187. ABSTRACT Refractoriness to antiseizure medications is still a major concern in the pharmacotherapy of epilepsy. For this reason,...
Orally administered Cannabigerol (CBG) in rats: Cannabimimetic actions, anxiety-like behavior, and inflammation-induced pain
Pharmacol Biochem Behav. 2024 Sep 23:173883. doi: 10.1016/j.pbb.2024.173883. Online ahead of print. ABSTRACT Cannabigerol (CBG) is a phytocannabinoid found in cannabis that is promoted for...
Emergence of semi-synthetic cannabinoids in cannabis products seized in Eastern Denmark over a 6-year period
J Forensic Sci. 2024 Sep 20. doi: 10.1111/1556-4029.15631. Online ahead of print. ABSTRACT Semi-synthetic cannabinoids (SSCs) are derivatives of phytocannabinoids with slight chemical modifications. SSCs...
Comparison and identification of aroma components in 21 kinds of frankincense with variety and region based on the odor intensity characteristic spectrum constructed by HS-SPME-GC-MS combined with E-nose
Food Res Int. 2024 Nov;195:114942. doi: 10.1016/j.foodres.2024.114942. Epub 2024 Aug 20. ABSTRACT Frankincense is an important seasoning and spice known for its distinctive and intricate...
Cannabinoids in the Inflamed Synovium Can Be a Target for the Treatment of Rheumatic Diseases
Int J Mol Sci. 2024 Aug 29;25(17):9356. doi: 10.3390/ijms25179356. ABSTRACT The management of rheumatic diseases has noticeably changed in recent years with the development of...
beta-Caryophyllene, a dietary phytocannabinoid, alleviates high-fat diet-induced hepatic steatosis in mice via AMPK activation
Biosci Biotechnol Biochem. 2024 Sep 13:zbae129. doi: 10.1093/bbb/zbae129. Online ahead of print. ABSTRACT β-Caryophyllene (BCP), a dietary phytocannabinoid, significantly suppresses palmitate-induced lipid accumulation in human...
Tea Prepared from Dried Cannabis: What Do We Drink?
J Agric Food Chem. 2024 Sep 12. doi: 10.1021/acs.jafc.4c05940. Online ahead of print. ABSTRACT Besides many other uses, dried Cannabis may be used for “tea”...
Genome-wide identification of cannabinoid biosynthesis genes in non-drug type Cannabis (Cannabis sativa L.) cultivar
J Cannabis Res. 2024 Sep 7;6(1):35. doi: 10.1186/s42238-024-00246-8. ABSTRACT BACKGROUND: Cannabis sativa cultivars can be classified as marijuana or hemp, depending on its amount of...
Identification and functional analysis of terpene synthases revealing the secrets of aroma formation in Chrysanthemum aromaticum
Int J Biol Macromol. 2024 Sep 5:135377. doi: 10.1016/j.ijbiomac.2024.135377. Online ahead of print. ABSTRACT C. aromaticum is widely cultivated for its aromatic, medicinal, and tea-applicable...
Multi-level therapeutic actions of cannabidiol in ketamine-induced schizophrenia psychopathology in male rats
Neuropsychopharmacology. 2024 Sep 6. doi: 10.1038/s41386-024-01977-1. Online ahead of print. ABSTRACT Repeated administration of ketamine (KET) has been used to model schizophrenia-like symptomatology in rodents,...
Medicinal cannabis extracts are neuroprotective against Aβ1-42-mediated toxicity in vitro
Basic Clin Pharmacol Toxicol. 2024 Sep 7. doi: 10.1111/bcpt.14078. Online ahead of print. ABSTRACT BACKGROUND: Phytocannabinoids inhibit the aggregation and neurotoxicity of the neurotoxic Alzheimer’s...
Medicinal cannabis extracts are neuroprotective against Aβ1-42-mediated toxicity in vitro
Basic Clin Pharmacol Toxicol. 2024 Sep 7. doi: 10.1111/bcpt.14078. Online ahead of print. ABSTRACT BACKGROUND: Phytocannabinoids inhibit the aggregation and neurotoxicity of the neurotoxic Alzheimer’s...