Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011-2012

Nutrients. 2022 Sep 29;14(19):4060. doi: 10.3390/nu14194060.

ABSTRACT

BACKGROUND: Low muscle strength is a predictor of mortality in older adults. Although the evidence concerning hyperglycemia is limited, evidence shows that omega-3 (ω-3) intake may be positively associated with muscle strength. However, the association between plasma ω-3 and muscle strength in older adults according to glycohemoglobin (HbA1c) levels has not yet been investigated.

OBJECTIVE: To evaluate whether plasma ω-3 levels are associated with handgrip strength in individuals over 50 years according to HbA1c levels.

METHODS: This cross-sectional study included 950 older adults (50-85 years) from NHANES 2011-2012. Linear regression analysis was performed to evaluate the association between plasma ω-3 and handgrip strength in individuals with elevated (≥5.7%) or normal HbA1c levels after adjustments for confounders.

RESULTS: Total plasma ω-3, docosahexaenoic acid, eicosapentaenoic acid and alpha-linolenic acid were not associated with handgrip strength in older adults regardless of HbA1c levels.

CONCLUSION: Plasma ω-3 levels are not associated with handgrip strength in individuals over 50 years old independent of HbA1c levels.

PMID:36235713 | PMC:PMC9572262 | DOI:10.3390/nu14194060