Compensatory role of endogenous sulfur dioxide in nitric oxide deficiency-induced hypertension
Redox Biol. 2021 Nov 18;48:102192. doi: 10.1016/j.redox.2021.102192. Online ahead of print. ABSTRACT OBJECTIVE: This study aimed to determine the communicational pattern of gaseous signaling molecules...
Management of central hemodynamic and endothelial function disturbances in patients with myocardial infarction combined with metabolic syndrome
Pol Merkur Lekarski. 2021 Oct 22;49(293):325-328. ABSTRACT On a global scale, myocardial infarction (MI) remains one of the most important cardiological challenges of today due...
Oral L-Arginine (5 g/day) for 14 Days Improves Microcirculatory Function in Healthy Young Women and Healthy and Type 2 Diabetes Mellitus Elderly Women
J Vasc Res. 2021 Nov 16:1-10. doi: 10.1159/000519428. Online ahead of print. ABSTRACT OBJECTIVE: The aim of this study was to investigate the effect of...
Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
Exp Neurol. 2021 Nov 12;348:113923. doi: 10.1016/j.expneurol.2021.113923. Online ahead of print. ABSTRACT Arginase 1 (A1) is the enzyme that hydrolyzes the amino acid, L-arginine, to...
Roles of Endothelial Motilin Receptor and Its Signal Transduction Pathway in Motilin-Induced Left Gastric Artery Relaxation in Dogs
Front Physiol. 2021 Oct 28;12:770430. doi: 10.3389/fphys.2021.770430. eCollection 2021. ABSTRACT Background: Motilin increases left gastric artery (LGA) blood flow in dogs via the endothelial motilin...
Folic acid, either solely or combined with L-citrulline, improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs
Physiol Rep. 2021 Nov;9(21):e15096. doi: 10.14814/phy2.15096. ABSTRACT Concomitant with developing pulmonary hypertension (PH), newborn piglets exposed to chronic hypoxia develop pulmonary vascular NO signaling impairments....
SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1
Atherosclerosis. 2021 Nov 8;340:1-11. doi: 10.1016/j.atherosclerosis.2021.11.006. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Human vascular smooth muscle cells (HA-VSMCs) are an important cell type...
Cyanidin-3-O-glucoside supplementation ameliorates metabolic insulin resistance via restoration of nitric oxide-mediated endothelial insulin transport
Mol Nutr Food Res. 2021 Nov 28:e2100742. doi: 10.1002/mnfr.202100742. Online ahead of print. ABSTRACT SCOPE: Anthocyanin cyanidin-3-O-glucoside (Cy3G) has a great potential in prevention of...
Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Placenta
Int J Endocrinol. 2021 Nov 15;2021:5017362. doi: 10.1155/2021/5017362. eCollection 2021. ABSTRACT Preeclampsia (PE) is one of the commonest causes for maternal and fetal morbidity and...
Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats
Biol Pharm Bull. 2021;44(12):1860-1865. doi: 10.1248/bpb.b21-00547. ABSTRACT An electrical communication between the endothelial and smooth muscle cells via gap junctions, which provides the signaling pathway...
Hypolipaemic nutraceutics: red yeast rice and Armolipid, berberine and bergamot
Ann Agric Environ Med. 2021 Mar 18;28(1):81-88. doi: 10.26444/aaem/130629. Epub 2020 Dec 2. ABSTRACT INTRODUCTION: Increased serum cholesterol levels constitute one of the main risk...
Doctor, Do You Know Red Yeast Rice?
Praxis (Bern 1994). 2021;110(4):207-220. doi: 10.1024/1661-8157/a003617. ABSTRACT Doctor, Do You Know Red Yeast Rice? Abstract. We present cases of patients with high total cholesterol who...
Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial
Asia Pac J Clin Nutr. 2021 Sep;30(3):424-435. doi: 10.6133/apjcn.202109_30(3).0009. ABSTRACT BACKGROUND AND OBJECTIVES: Red yeast rice contains monacolin K, an inhibitor of cholesterol synthesis, and...
Nutraceutical Combinations in Hypercholesterolemia: Evidence from Randomized, Placebo-Controlled Clinical Trials
Nutrients. 2021 Sep 8;13(9):3128. doi: 10.3390/nu13093128. ABSTRACT There is an increasing number of nutraceutical combinations (NCs) on the market for hypercholesterolemia, although clinical trials to...
Acute and Long Term Effects of a Nutraceutical Combination on Lipid Profile, Glucose Metabolism and Vascular Function in Patients with Dyslipidaemia with and Without Cigarette Smoking
High Blood Press Cardiovasc Prev. 2021 Sep;28(5):483-491. doi: 10.1007/s40292-021-00468-4. Epub 2021 Sep 13. ABSTRACT INTRODUCTION: Lifestyle changes present a fundamental role in cardiovascular prevention. Nutraceuticals...