Effects of Supplementation with Folic Acid and Its Combinations with Other Nutrients on Cognitive Impairment and Alzheimer’s Disease: A Narrative Review
Nutrients. 2021 Aug 26;13(9):2966. doi: 10.3390/nu13092966. ABSTRACT Cognitive impairment and Alzheimer’s Disease, among other cognitive dysfunctions, has been recognized as a major public health problem....
Contrasting Metabolic Insufficiency in Aging and Dementia
Aging Dis. 2021 Jul 1;12(4):1081-1096. doi: 10.14336/AD.2021.0104. eCollection 2021 Jul. ABSTRACT Metabolic insufficiency and neuronal dysfunction occur in normal aging but is exaggerated in dementia...
Migraine and Vascular Risk: An Update
Neurol India. 2021 Mar-Apr;69(Supplement):S83-S90. doi: 10.4103/0028-3886.315974. ABSTRACT BACKGROUND: Migraine is a common neurological disorder with significant morbidity and disability. There is growing evidence that migraine...
Association Between Homocysteine and Vitamin Levels in Demented Patients
J Alzheimers Dis. 2021;81(4):1781-1792. doi: 10.3233/JAD-201481. ABSTRACT BACKGROUND: Although it is known that the nutritional status among elderly persons and, in particular, patients with dementia,...
Ubiquinol Supplementation Improves Gender-Dependent Cerebral Vasoreactivity and Ameliorates Chronic Inflammation and Endothelial Dysfunction in Patients with Mild Cognitive Impairment
Antioxidants (Basel). 2021 Jan 20;10(2):143. doi: 10.3390/antiox10020143. ABSTRACT Ubiquinol can protect endothelial cells from multiple mechanisms that cause endothelial damage and vascular dysfunction, thus contributing...
Safety of water extract of Cistanche tubulosa stems as a Novel food pursuant to Regulation (EU) 2015/2283
EFSA J. 2021 Jan 15;19(1):e06346. doi: 10.2903/j.efsa.2021.6346. eCollection 2021 Jan. ABSTRACT Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods...
Plasma Vitamin B12 Levels, High-Dose Vitamin B12 Treatment, and Risk of Dementia
J Alzheimers Dis. 2021;79(4):1601-1612. doi: 10.3233/JAD-201096. ABSTRACT BACKGROUND: It is controversial whether B12 deficiency causes dementia or B12 treatment can prevent dementia. OBJECTIVE: To assess...
Hydrogen sulfide attenuates hyperhomocysteinemia-induced blood-brain barrier permeability by inhibiting MMP-9
Int J Neurosci. 2021 Feb 1:1-11. doi: 10.1080/00207454.2020.1860967. Online ahead of print. ABSTRACT Backgroud: Hyperhomocysteinemia (HHcy) is implicated in various neurovascular disorders including vascular dementia,...
Lack of direct involvement of a diazepam long-term treatment in the occurrence of irreversible cognitive impairment: a pre-clinical approach
Transl Psychiatry. 2021 Dec 3;11(1):612. doi: 10.1038/s41398-021-01718-8. ABSTRACT Several observational studies have found a link between the long-term use of benzodiazepines and dementia, which remains...