Protective and anti-oxidative effects of curcumin and resveratrol on Aβ-oligomer-induced damage in the SH-SY5Y cell line
J Neurol Sci. 2022 Aug 1;441:120356. doi: 10.1016/j.jns.2022.120356. Online ahead of print. ABSTRACT Alzheimer’s disease (AD) is a degenerative disorder characterized by the loss of...
The emerging role of quercetin in the treatment of chronic pain
Curr Neuropharmacol. 2022 Aug 12. doi: 10.2174/1570159X20666220812122437. Online ahead of print. ABSTRACT Despite much research efforts being devoted to design alternative pharmacological interventions, chronic pain...
The analgesic effects of β-elemene in rats with neuropathic pain by inhibition of spinal astrocytic ERK activation
Mol Pain. 2022 Apr;18:17448069221121562. doi: 10.1177/17448069221121562. ABSTRACT Neuropathic pain takes a heavy toll on individual well-being, while current therapy is far from desirable. Herein, we...
Chlorogenic acid: A dietary phenolic acid with promising pharmacotherapeutic potential
Curr Med Chem. 2022 Aug 16. doi: 10.2174/0929867329666220816154634. Online ahead of print. ABSTRACT Phenolic acids are now receiving a great deal of interest as pervasive...
Complex effects of physical exertion with dietary supplements Cartilox in pain syndrome effectiveness and safety evaluation
Vopr Kurortol Fizioter Lech Fiz Kult. 2022;99(4):20-28. doi: 10.17116/kurort20229904120. ABSTRACT A promising direction of osteoarthritis (OA) therapy is currently being considered pharmaceutical compositions of Symptomatic...
Multifaceted role of polyphenols in the treatment and management of neurodegenerative diseases
Chemosphere. 2022 Aug 16:136020. doi: 10.1016/j.chemosphere.2022.136020. Online ahead of print. ABSTRACT Neurodegenerative diseases (NDDs) are conditions that cause neuron structure and/or function to deteriorate over...
A Sensitive Spectrofluorimetric Method for Curcumin Analysis
J Fluoresc. 2022 May 8. doi: 10.1007/s10895-022-02947-w. Online ahead of print. ABSTRACT Curcumin (CUR), a natural polyphenolic compound extracted from the rhizomes of Curcuma longa,...
Experimentally designed chemometric models for the assay of toxic adulterants in turmeric powder
RSC Adv. 2022 Mar 23;12(15):9087-9094. doi: 10.1039/d2ra00697a. eCollection 2022 Mar 21. ABSTRACT Turmeric is an indispensable culinary spice in different cultures and a principal component...
Safety Evaluation of Oleoresin-Based Turmeric Formulation: Assessment of Genotoxicity and Acute and Subchronic Oral Toxicity
Biomed Res Int. 2022 Mar 31;2022:5281660. doi: 10.1155/2022/5281660. eCollection 2022. ABSTRACT Turmeric rhizome (Curcuma longa L.) has been used without concern for safety as a...
Benefits of Curcumin in the Vasculature: A Therapeutic Candidate for Vascular Remodeling in Arterial Hypertension and Pulmonary Arterial Hypertension?
Front Physiol. 2022 Apr 1;13:848867. doi: 10.3389/fphys.2022.848867. eCollection 2022. ABSTRACT Growing evidence suggests that hypertension is one of the leading causes of cardiovascular morbidity and...
Biological control: An effective approach against nematodes using black pepper plants (Piper nigrum L.)
Saudi J Biol Sci. 2022 Apr;29(4):2047-2055. doi: 10.1016/j.sjbs.2022.01.004. Epub 2022 Jan 6. ABSTRACT Black pepper (Piper nigrum L.) is one of the oldest spices in...
Superior Pharmacokinetic Profile of an Innovative, Next Generation Curcumin Formula
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5807. ABSTRACT INTRODUCTION: Curcumin is the major bioactive component of turmeric or Curcuma longa L., a widely used...
Colon Cancer Cell Death by Synergistic Activity of Phytochemicals is Modulated by Increased ROS, Activation of AMPK, and Inhibition of mTORC1
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.0R812. ABSTRACT Colorectal cancer (CRC) is the second leading cause of cancer-related death in the United States, and...
Benefits of Curcumin in the Vasculature: A Therapeutic Candidate for Vascular Remodeling in Arterial Hypertension and Pulmonary Arterial Hypertension?
Front Physiol. 2022 Apr 1;13:848867. doi: 10.3389/fphys.2022.848867. eCollection 2022. ABSTRACT Growing evidence suggests that hypertension is one of the leading causes of cardiovascular morbidity and...
The terminal enzymatic step in piperine biosynthesis is co-localized with the product piperine in specialized cells of black pepper (Piper nigrum L.)
Plant J. 2022 May 30. doi: 10.1111/tpj.15847. Online ahead of print. ABSTRACT Piperine (1-piperoyl-piperidine) is responsible for the pungent perception of dried black pepper (Piper...