The Potential Effect of Blueberry on Cognitive Health and Mood State Based on Human Intervention Studies: Systematic review & Mini Meta-analysis
CNS Neurol Disord Drug Targets. 2022 Jun 8. doi: 10.2174/1871527321666220608085852. Online ahead of print. ABSTRACT BACKGROUND: Blueberries are known for their high content of several...
Neuroprotective potential of curcuminoids in modulating Alzheimer’s Disease via multiple signaling pathways
Curr Med Chem. 2022 Jun 7. doi: 10.2174/0929867329666220607161328. Online ahead of print. ABSTRACT Alzheimer’s disease (AD) is a progressive and frequent neurodegenerative disease of elderly...
Synthesis and Anti-Neuroinflammatory Activity of 1,7-diphenyl-1,4-heptadien-3-ones in LPS-Stimulated BV2 Microglia Via Inhibiting NF-κB/MAPK Signaling Pathways
Molecules. 2022 May 31;27(11):3537. doi: 10.3390/molecules27113537. ABSTRACT A series of 1,7-diphenyl-1,4-heptadien-3-ones with various substituents (HO-, CH3O-, CH3-, Cl-) on the phenyl rings were synthesized and...
Quercetin binding accelerates prion fibrillation into proteinase sensitive and loosely structured amyloids
Biomed Pharmacother. 2022 Jul;151:113177. doi: 10.1016/j.biopha.2022.113177. Epub 2022 May 27. ABSTRACT Amyloidoses are caused by the deposition of amyloid fibrils ascribed to protein misfolding. In...
Ameliorative effects of phytomedicines on Alzheimer’s patients
Curr Alzheimer Res. 2022 Jun 10. doi: 10.2174/1567205019666220610155608. Online ahead of print. ABSTRACT INTRODUCTION: Alzheimer’s Disease (AD) is a progressive, neurodegenerative disease that severely affects...
Application of curcumin nanoformulations in Alzheimer’s disease: prevention, diagnosis and treatment
Nutr Neurosci. 2022 Jun 11:1-16. doi: 10.1080/1028415X.2022.2084550. Online ahead of print. ABSTRACT Objectives: Alzheimer’s disease (AD) is a serious neurodegenerative disease. Although many therapeutic strategies...
Oxidative Balance Score during Pregnancy Is Associated with Oxidative Stress in the CANDLE Study
Nutrients. 2022 Jun 1;14(11):2327. doi: 10.3390/nu14112327. ABSTRACT The objective of this study was to calculate an oxidative balance score (OBS) utilizing diet and lifestyle information...
GA&HA-Modified Liposomes for Co-Delivery of Aprepitant and Curcumin to Inhibit Drug-Resistance and Metastasis of Hepatocellular Carcinoma
Int J Nanomedicine. 2022 Jun 7;17:2559-2575. doi: 10.2147/IJN.S366180. eCollection 2022. ABSTRACT BACKGROUND: Tumor microenvironment (TME) plays a vital role in the development of hepatocellular carcinoma...
Intrinsically Bioactive Manganese-eumelanin Nanocomposites Mediated Antioxidation and Anti-neuroinflammation for Targeted Theranostics of Traumatic Brain Injury
Adv Healthc Mater. 2022 Jun 13:e2200517. doi: 10.1002/adhm.202200517. Online ahead of print. ABSTRACT Overproduced reactive oxygen species and the induced oxidative stress and neuroinflammation often...
Curcumin alleviates the manganese-induced neurotoxicity by promoting autophagy in rat models of manganism
Beijing Da Xue Xue Bao Yi Xue Ban. 2022 Jun 18;54(3):400-411. ABSTRACT OBJECTIVE: To investigate the protective effects of curcumin(CUR) and its mechanism on a...
Recent updates in curcumin delivery
J Liposome Res. 2022 Jun 14:1-12. doi: 10.1080/08982104.2022.2086567. Online ahead of print. ABSTRACT Curcumin is a natural component extracted from the rhizomes of turmeric (Curcuma...
Novel multifunctional bionanoparticles modified with sialic acid for stroke treatment
Int J Biol Macromol. 2022 Jun 15:S0141-8130(22)01306-X. doi: 10.1016/j.ijbiomac.2022.06.102. Online ahead of print. ABSTRACT Oxidative stress and inflammation are two key pathophysiological mechanisms that lead...
Role of endoplasmic reticulum stress in cadmium-induced hepatocyte apoptosis and the protective effect of quercetin
Ecotoxicol Environ Saf. 2022 Jun 14;241:113772. doi: 10.1016/j.ecoenv.2022.113772. Online ahead of print. ABSTRACT Cadmium (Cd) is one of the most toxic environmental pollutants. Quercetin (Que)...
Curcumin-Pretreated Adipose-Derived Stem Cells Enhance the Neuroprotective Ability to Repair Rheumatoid Arthritis-Induced Damage in the Rat Brain
Am J Chin Med. 2022 Jun 17:1-16. doi: 10.1142/S0192415X22500549. Online ahead of print. ABSTRACT Neurodegenerative diseases have become increasingly prevalent in the aged population. Rheumatoid...
Vanillin crosslinked chitosan films: The states of water and the effect of carriers on curcumin uptake
Carbohydr Polym. 2022 Sep 15;292:119725. doi: 10.1016/j.carbpol.2022.119725. Epub 2022 Jun 11. ABSTRACT In this work, chitosan chains were crosslinked with different contents of vanillin (Van),...