[Corrigendum] Quercetin protects rat cortical neurons against traumatic brain injury
Mol Med Rep. 2022 Jul;26(1):216. doi: 10.3892/mmr.2022.12732. Epub 2022 May 11. ABSTRACT Subsequently to the publication of the above paper, an interested reader drew to...
Screening of Non-Purine Ligands Binding to Adenosine Receptors A1 , A2A , A2B , and A3
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R4816. ABSTRACT Adenosine receptors (ARs) are G-protein coupled receptors (GPCRs) which have been shown to have therapeutic potential....
The Effects of Blackcurrant and Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R2805. ABSTRACT BACKGROUND: Cardiovascular disease (CVD) is the number one cause of morbidity and mortality for both men...
Potential Drug Therapy For Fragile X Tremor/Ataxia Syndrome
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R6346. ABSTRACT Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurological disorder that affects carriers of the alleles...
The Effect of Curcumin on Idiopathic Parkinson Disease: A Clinical and Skin Biopsy Study
J Neuropathol Exp Neurol. 2022 May 13:nlac034. doi: 10.1093/jnen/nlac034. Online ahead of print. ABSTRACT There are currently no standardized therapies for Parkinson disease (PD). Curcumin...
The Effects of Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells: A Potential Cardioprotective and Neuroprotective Mechanism
Molecules. 2022 Apr 27;27(9):2789. doi: 10.3390/molecules27092789. ABSTRACT Oxidative stress is a key underlying factor in cognitive decline and atherosclerosis. Oxidative stress occurs at the cellular...
In-Vitro Antioxidant Assays and Computational Investigation of Phytoconstituents from Theobroma cacao Beans as Inhibitors of Neuro-Modulatory Enzymes
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7613. ABSTRACT Neurodegenerative disease (ND) is a heterogeneous group of disorders characterized by progressive deterioration of neuronal cells...
Curcumin attenuates LPS-induced sickness behavior and fever LPS-induced in rats by modulating Nrf2 activity
Neurosci Lett. 2022 May 11:136680. doi: 10.1016/j.neulet.2022.136680. Online ahead of print. ABSTRACT Lipopolysaccharide (LPS) is a potent inducer of inflammation, triggering behavioral changes and fever....
Flavonoids as Potential Anti-Inflammatory Molecules: A Review
Molecules. 2022 May 2;27(9):2901. doi: 10.3390/molecules27092901. ABSTRACT Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits, cereals, nuts, herbs, seeds, stems, and flowers...
Biodegradable Nanoparticles Loaded with Levodopa and Curcumin for Treatment of Parkinson’s Disease
Molecules. 2022 Apr 28;27(9):2811. doi: 10.3390/molecules27092811. ABSTRACT Background: Parkinson’s disease (PD) is the second most common age-related neurodegenerative disorder. Levodopa (L-DOPA) remains the gold-standard drug...
Platelet Activating Factor Receptor Exaggerates Microglia-Mediated Microenvironment by IL10-STAT3 Signaling: A Novel Potential Biomarker and Target for Diagnosis and Treatment of Alzheimer’s Disease
Front Aging Neurosci. 2022 Apr 28;14:856628. doi: 10.3389/fnagi.2022.856628. eCollection 2022. ABSTRACT BACKGROUND: Early diagnosis and effective intervention are the keys to delaying the progression of...
Curcumin Restrains Oxidative Stress of After Intracerebral Hemorrhage in Rat by Activating the Nrf2/HO-1 Pathway
Front Pharmacol. 2022 Apr 27;13:889226. doi: 10.3389/fphar.2022.889226. eCollection 2022. ABSTRACT Intracerebral hemorrhage (ICH), a severe hemorrhagic stroke, induces cerebral oxidative stress and severe secondary neurological...
Curcumin inhibits cerebral ischaemia-reperfusion injury and cell apoptosis in rats through the ERK-CHOP-caspase-11 pathway
Pharm Biol. 2022 Dec;60(1):854-861. doi: 10.1080/13880209.2022.2069271. ABSTRACT CONTEXT: Curcumin has a significant effect on cerebral ischaemia-reperfusion injury (CIRI). However, the underlying mechanism is less studied....
Curcumin: reclaiming the lost ground against cancer resistance
Cancer Drug Resist. 2021 Jun 19;4(2):298-320. doi: 10.20517/cdr.2020.92. eCollection 2021. ABSTRACT Curcumin, a polyphenol, has a wide range of biological properties such as anticancer, antibacterial,...
Targeting the Pathological Hallmarks of Alzheimer’s Disease Through Nanovesicle-aided Drug Delivery Approach
Curr Drug Metab. 2022 May 26. doi: 10.2174/1389200223666220526094802. Online ahead of print. ABSTRACT Introduction- Nanovesicle technology is making a huge contribution to the progress of...