In vitro assessment of physiological traits and ROS detoxification pathways involved in tolerance of Damask rose genotypes under salt stress
Sci Rep. 2023 Oct 18;13(1):17795. doi: 10.1038/s41598-023-45041-2. ABSTRACT Rosa damascena is one of the most important medicinal and ornamental plants in Iran which is tolerant...
Anxiogenic doses of rapamycin prevent URB597-induced anti-stress effects in socially defeated mice
Neurosci Lett. 2023 Oct 16:137519. doi: 10.1016/j.neulet.2023.137519. Online ahead of print. ABSTRACT Repeated exposure to psychosocial stress modulates the endocannabinoid system, particularly anandamide (AEA) signaling...
The Effect of Route of Administration and Vehicle on the Pharmacokinetics of THC and CBD in Adult, Neonate, and Breastfed Sprague-Dawley Rats
Cannabis Cannabinoid Res. 2023 Oct 18. doi: 10.1089/can.2023.0121. Online ahead of print. ABSTRACT Introduction: Basic pharmacokinetic (PK) and pharmacodynamic models of the phytocannabinoids Δ-9-tetrahydrocannabinol (THC)...
The Effect of Route of Administration and Vehicle on the Pharmacokinetics of THC and CBD in Adult, Neonate, and Breastfed Sprague-Dawley Rats
Cannabis Cannabinoid Res. 2023 Oct 18. doi: 10.1089/can.2023.0121. Online ahead of print. ABSTRACT Introduction: Basic pharmacokinetic (PK) and pharmacodynamic models of the phytocannabinoids Δ-9-tetrahydrocannabinol (THC)...
Four Good Reasons Why Guys Should Eat More Soy
I’ve spent a great deal of my time and energy as a nutrition professional encouraging my clients, particularly men, to pursue a greater variety in...
Preventing and Managing Gout: Soy Foods May Play a Role
Gout is an extremely common form of inflammatory arthritis, affecting 4% of the U.S. population. Men, particularly as they age, are much more likely to...
Is Soy A High-Quality Muscle-Building Protein Source?
There are a relatively limited number of foods that contain significant amounts of complete plant-based protein, and soy foods such as tofu, tempeh, edamame, and...
Does Soy Lower Testosterone?
As someone who deals with this topic on a near-daily basis, I appreciate more than most the significant public interest surrounding the consumption of soy-based...
Co-occurrence of bipolar disorder and personality disorders in the United States: Prevalence, suicidality, and the impact of substance abuse
J Affect Disord. 2023 Oct 15:S0165-0327(23)01276-4. doi: 10.1016/j.jad.2023.10.087. Online ahead of print. ABSTRACT BACKGROUND: This study investigates prevalence rates of specific personality disorders (PDs) in...
Cannabis use disorder, suiscide attempts, and self-harm among adolescents: A national inpatient study across the United States
PLoS One. 2023 Oct 17;18(10):e0292922. doi: 10.1371/journal.pone.0292922. eCollection 2023. ABSTRACT BACKGROUND: Suicide is among the top three causes of adolescent mortality. There is a scarcity...
Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor
ACS Chem Neurosci. 2023 Oct 17. doi: 10.1021/acschemneuro.3c00530. Online ahead of print. ABSTRACT The emergence of synthetic cannabinoid receptor agonists (SCRAs) as illicit psychoactive substances...
Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor
ACS Chem Neurosci. 2023 Oct 17. doi: 10.1021/acschemneuro.3c00530. Online ahead of print. ABSTRACT The emergence of synthetic cannabinoid receptor agonists (SCRAs) as illicit psychoactive substances...
Using Latent Profile Analysis to Examine Cannabis Use Contexts: Associations with Use, Consequences, and Protective Behaviors
Subst Use Misuse. 2023 Oct 16:1-10. doi: 10.1080/10826084.2023.2267112. Online ahead of print. ABSTRACT OBJECTIVE: College students represent a large portion of the population, and report...
Analytical description of adolescent binge drinking patients
BMC Pediatr. 2023 Oct 16;23(1):512. doi: 10.1186/s12887-023-04325-2. ABSTRACT BACKGROUND: Binge drinking is a widespread health compromising behavior among adolescents and young adults, leading to significant...
Cannabinoids and endocannabinoids as therapeutics for nervous system disorders: preclinical models and clinical studies
Neural Regen Res. 2024 Apr;19(4):788-799. doi: 10.4103/1673-5374.382220. ABSTRACT Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a variety of effects in the...